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SISTEMI NANOPARTICELLARI PER LA VEICOLAZIONE DI FARMACI PER IL TRATTAMENTO DI PATOLOGIE CORRELATE ALLE INFEZIONI DA LEISHMANIA
The invention relates to polymeric nano particle as effective vehicles for compounds containing antimony, also antimonials, such as N-methylglucamine antimoniate (Glucantime®). More in particular, the active , used for the treatment of pathologies related to infection with Leishmania, was entrapped in the aqueous "core" of nanocapsules having an external layer, or "shell" of polylactic acid (PLA), that allow reducing cell toxicity and modulation of its biodistribution and of its biopharmaceutical properties, without altering its pharmacological effectiveness
Britti Domenico, Cosco Donato, Fresta Massimo, Paolino Donatella, Trapasso Elena
Donatella Paolino, received the degree in Pharmaceutical Chemistry and Technology from the University of Catania (Italy) in 1999. In 2003 shereceived the Ph.D. degree in “Pharmaceutical Technology of BioactiveSubstances” from the University of Palermo (Italy). Shereceived the Pharm.D. degree in Hospital Pharmacy from the University of Catania (Italy). Shegot the position of research fellow at the University of Catanzaro on 2005 and then she joined the Faculty of Medicine and Surgery of the University of Catanzaro as aggregate professor from 2007 to 2015, from 2015 sheis associate professor at the Department of Experimental and Clinic Medicine. Sheserves as a peer reviewer of a number of prestigious International journals (International Journal of Pharmaceutics, Nanomedicine, Journal of Controlled Release, Expert Opinion on Drug Delivery, etc.). Sheismember of the editorial board of “The Scientific World Journal”. The teaching staff of Donatella Paolino are: Advanced Pharmaceutical Technology, Chemistry of CosmeticProducts, ChemicalBiotechnology and PharmaceuticalNanotechnology, and sheisalso in the advisoryboard of the Doctorate Course of PharmaceuticalSciences - University of Catanzaro.
The current research interests of Donatella Paolino are the followings: innovative colloidal drug delivery systems for the selective delivery of drugs; colloidal carriers for topical drug administration; self-assembling supramolecular drug delivery systems. Sheis co-author of 120 full paper and more than 200 abstracts in International conferences/congresses. Sheis a member of various national and International scientific societies.
Stand C1 (pav. 5) - University Magna Graecia of Catanzaro
Data updated on 2018-12-04 - 10.56.27 am
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